Genetics
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Age-related hearing loss impacts one in three adults aged 64 to 75 in the US, and around half of these cases are down to faulty genes. Using older animals to mirror a human study, scientists successfully reversed hearing loss caused by one such gene.
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A Colombian man's novel genetic mutation that stalled the symptoms of his rare form of Alzheimer's for 20 years has been identified. The discovery could lead to therapies that boost people’s resilience against the debilitating disease.
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Fusarium fungus once decimated the world’s dominant Gros Michel bananas, so much so that the Cavendish variety became the global go-to. Now, as a new strain threatens its survival, approval of the very first GM Cavendish could prevent "bananageddon."
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The first draft of a human “pangenome,” mapping out DNA variations in our genes, has been published. Building on the existing reference genome by adding 1,000 new gene mutations and 120 million base pairs, it's crucial for future genetic research.
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A groundbreaking project has seen hundreds of scientists across the world uncover many mysteries of the evolution of mammals, work that may help us understand why humans are unique and what genetic changes may be key to some of our unique diseases.
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UK researchers have, for the first time, identified a genetic pathway in the brain that plays a key role in controlling anxiety, opening the door to the development of more effective treatments in the future.
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Researchers have discovered a gene in the testicular tissue in multiple mammals, including humans. Disabling it changed the shape and function of sperm and could lead to an oral contraceptive for men that would only work while it is administered.
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Genetic mutations can lead to diseases like cancer. In a new study, researchers have used the gene-editing technology CRISPR/Cas 9 in a less commonly used way, producing liver cancer tumors to better understand the genetic mutations underlying them.
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Human stem cells can differentiate into any human cell. But dedifferentiation, differentiation in reverse, is implicated in several diseases. Now, researchers have uncovered a mechanism key to the process of stem cell dedifferentiation.
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Antimicrobial resistance, particularly resistance to antibiotics, is a worldwide problem. A new study has, for the first time, shown how the consumption of antibiotics by an entire population can affect an individual's health.
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Research which shows why DNA is repaired in certain cells but not in others could help ward off the ravages of aging, and diseases including cancer. It all hinges on a protein group called the DREAM complex.
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Some cancer cells develop resistance to chemotherapy. Belgian scientists have investigated the cause of chemotherapy resistance and switched off the gene contributing to it, making cancer cells more sensitive to treatment.
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