Drug
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A gene called MYC is implicated in the majority of cancers, but unfortunately it’s often considered “undruggable.” In a new study scientists have developed a molecule that chops up the RNA of this gene, effectively clearing cancer in mice.
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A Phase 3 clinical trial of the drug donanemab has shown it can significantly slow cognitive and functional decline in people with early-stage Alzheimer’s disease, compared with existing treatments.
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Melbourne’s Monash University has commenced a Phase 1 clinical trial to test a novel inhaled powder designed to prevent postpartum hemorrhage, a serious complication of childbirth that causes tens of thousands of deaths worldwide.
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Missing medications or not taking them as required can have costly results. Bioengineers at Rice University may have the solution to missed medications, using advanced technology to create a system that delivers time-released drugs.
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Heart failure is commonly complicated by sleep apnea, a co-morbidity that further reduces a person’s lifespan. A promising new drug could treat heart failure and sleep apnea by targeting the nervous activity that drives both.
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Ovarian cancer is marked by low survival rates and a high rate of recurrence despite treatment. But a promising cancer-fighting drug is undergoing clinical trials, providing hope for women whose cancer has returned following chemotherapy.
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Humans have bitter taste receptors not only in their mouths but in their lungs, too. Researchers have exploited these receptors’ innate ability to dilate the airways to create a potent new drug that may change how we treat diseases like asthma and COPD.
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High cholesterol levels are a common and potentially deadly health problem, but a new drug could help more people manage the condition. An experimental pill has been shown to reduce levels of “bad” cholesterol by 60% in a phase 2 clinical trial.
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There are plenty of studies into the effects of cannabis on health. But a first-of-its-kind US study has found a connection between different patterns of cannabis use by patients and how well they recover from surgery.
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Male contraceptives have traditionally been limited to condoms and vasectomies. Now scientists have demonstrated a promising new method that takes the form of a pill that can be taken just before sex, greatly reducing fertility for 24 hours.
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Scientists at MIT have developed bottlebrush-shaped molecules that can carry groups of different cancer drugs in just the right ratios. Tests in mice showed significantly improved outcomes compared to just giving the drugs loose.
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In an ideal world, managing diabetes wouldn’t involve insulin injections but just popping a pill. Now a team of scientists has demonstrated an oral tablet that’s self-propelled by chemical “micromotors” to deliver insulin in the colon of rats.
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